Just imagine wrestling with God. There you are the created wrestling with the creator. Now that sounds like a fun deal, wrestling with God. There is a certain person in the Bible that wrestled with a angel. Do you know who that was? Fuel for thought.
There is one way that you can wrestle with God. Prayer. It's good to come boldly before the Throne of Grace and cry out to God for those things that we need God's intervention in. You might be saying not so. Well look at it this way, you can rend your garments, or rend your heart. what is it to rend your heart?
Personally I believe that God loves it when we come before Him and wrestle with Him about a specific matter. I mean if you were seeking God for healing would you only ask once or continue to ask until you were healed? What if you were praying about one of your children around a specific matter of great importance, would you ask once and that's it?
Pray without ceasing. 1 Th 5:17